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Cat. No. Product Name Target Signaling Pathways
T8737 GR 125743

5-HT Receptor GPCR/G Protein; Neuroscience
GR 125743 是选择性的5-HT1B/1D 受体拮抗剂,与野生型的人 h5-HT1B 和 5-HT1D 结合的pKi 分别为 8.85 和 8.31,可用于帕金森病和心血管疾病的研究。
T2150 Guanfacine hydrochloride

盐酸胍法辛,Tenex,Intuniv,Guanfacine

Adrenergic Receptor GPCR/G Protein; Neuroscience
Guanfacine hydrochloride (Intuniv) 是一种 α2A 肾上腺素受体激动剂,Kd=31 nM,具有抗高血压作用。
T12054L MK-0249 FA

MK-0249 FA(862309-06-6 Free base)

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
MK-0249 FA 是一种具有口服活性、选择性和高效性的组胺 H3 反向激动剂,可用于研究成人注意力缺陷、多动症神经分裂和认知障碍。
T34752 Samelisant dihydrochloride

SUVN-G3031,SUVN-G 3031,SUVN G3031,SUVN-G3031 HCl

Samelisant dihydrochloride (SUVN-G3031) is a antagonist of histamine H3 receptor with potential for the treatment of cognitive impairment, dementia, attention deficit hyperactivity disorder, epilepsy, sleep disorders, obesity, schizophrenia, eating disorders, and pain.
T35591 Guanfacine-13C,15N3

Guanfacine-13C,15N3

Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A-, α2B-, and α2C-ARs, respectively, in a radioligand binding assay.1It has EC50values of 52, 288, and 602 nM for α2A-, α2B-, and α2C-ARs, respectively, for stimulated [35S]GTPγS binding. It also binds to imidazoline receptor 1 (Ki= 19 nM in a radioligand binding assay).2Guanfacin...

化合物

GR 125743
Cat.No: T8737
Synonym:
Target: 5-HT Receptor
Guanfacine hydrochloride
Cat.No: T2150
Synonym: 盐酸胍法辛,Tenex,Intuniv,Guanfacine
Target: Adrenergic Receptor
MK-0249 FA
Cat.No: T12054L
Synonym: MK-0249 FA(862309-06-6 Free base)
Target: Histamine Receptor
Samelisant dihydrochloride
Cat.No: T34752
Synonym: SUVN-G3031,SUVN-G 3031,SUVN G3031,SUVN-G3031 HCl
Target:
Guanfacine-13C,15N3
Cat.No: T35591
Synonym: Guanfacine-13C,15N3
Target:
TargetMol Loading
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